NIH awards $170 million for precision nutrition study

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Thursday January 20 2022

The Nutrition for Precision Health study leverages the large and diverse data platform of the All of Us Research Program of the National Institutes of Health.

The National Institutes of Health is awarding $170 million over five years, pending the availability of funds, to clinics and centers across the country for a new study that will develop algorithms to predict individual responses to food and dietary routine. Nutrition for Precise Health supported by the All of Us Research (NPH) Program It will recruit a diverse group of 10,000 participants who are part of the National Institutes of Health all of us Research program to inform more personalized nutrition recommendations.

The initiative includes 11 new awards and provides additional funds to three existing National Institutes of Health all of us Research Program Awards. NPH is an NIH-wide effort managed by the NIH Common Fund and the first independent study to invite diverse participants from all of us a program.

“We know that nutrition, just like medicine, is not a one-size-fits-all,” said Holly Nicastro, PhD, MPH, coordinator of NPH. “NPH will take into account an individual’s genetics, gut microbes, other lifestyle factors, biological, environmental, or social factors to help each individual develop eating recommendations that improve overall health.”

A major challenge in nutrition accuracy is the inability to combine the many factors that influence how individuals respond to diet into a personalized feeding regime. These potential factors include the microbiome – the community of microbes that live in our gut, metabolism, nutritional status, genetics, and environment. The way these factors interact to affect health is still poorly understood.

To address these gaps, NPH will collect new data on many potential predictive factors and combine it with existing data all of us A database to develop a more complete picture of how individuals respond to different foods or dietary routines. By developing this large study of precision nutrition research, NPH will complement ongoing nutrition research efforts across the National Institutes of Health and implement components of the 2020-2030 Strategic Plan for Nutrition Research of the National Institutes of Health. NPH data will be merged into a file all of us Research Workbench is widely available to allow researchers to make discoveries that improve health and prevent or treat diseases and conditions affected by nutrition.

“the all of us Josh Denny, MD, CEO of all of us. “We are so happy all of us He has a role in developing in-depth nutrition research and advancing nutrition accuracy by serving as a platform for this unique initiative.”

all of us It will contribute current data from participants who have agreed to participate in the NPH study, including genomics, associated electronic health records and survey data, such as information on daily living experiences, family health, and more. These data links will make NPH one of the largest and most diverse micro-nutrition studies to date.

The NPH program includes multiple institutes and centers within the National Institutes of Health, including the NIH Common Fund; all of us research program; Nutrition Research Office; National Institute of Diabetes and Digestive and Kidney Diseases. National Heart, Lung, and Blood Institute; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute; The National Center for the Development of Translational Sciences.

The 14 awards will create the NPH consortium including six clinical centers, a center for diet assessment, a center for metabolic processes and clinical examinations, a center for microbiome and metagenomics, a multimedia data modeling center, a bioinformatics center, a research coordination center, and additional curator support. all of us Infrastructure.

Watch the Nutrition for Accurate Health overview video, powered by All of Us Research® To find out more about this initiative.

About the National Institutes of Health Joint Fund: The NIH Common Fund encourages collaboration and supports a series of exceptionally high-impact NIH programs. Mutual Fund programs are managed by the Office of Strategic Coordination in the Division of Program Coordination, Planning and Strategic Initiatives within the Office of the Director of the National Institutes of Health in partnership with the NIH institutes, centers, and offices. More information is available on the mutual fund website:

about the all of us Research Program: a task all of us The research program aims to accelerate health research and medical advances, enabling individual prevention, treatment, and care for all of us. The program will partner with 1 million or more people across the United States to build the most diverse biomedical data resources of their kind, to help researchers gain better insights into the biological, environmental and behavioral factors that affect health. For more information, visit,, and

About the National Institutes of Health (NIH):NIH, the country’s medical research agency, includes 27 institutes and centers and is part of the US Department of Health and Human Services. The National Institutes of Health is the primary federal agency that conducts and supports basic, clinical, and polymedical research, investigating the causes, treatments, and treatment of both common and rare diseases. For more information about the National Institutes of Health and its programs, visit

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